Medscape Nephrology Headlines

Reversal of Proteinuric Renal Disease and the Emerging Role of Endothelin

Thu, 24 Jul 2008 12:00:00 EDT

Endothelin has a prominent role in the pathogenesis of proteinuric renal disease. The current article examines how endothelin promotes renal disease as well as medications that can antagonize endothelin.
Nature Clinical Practice Nephrology

Everolimus Potential Alternative for Metastatic Renal Cell Carcinoma

Thu, 24 Jul 2008 08:49:20 EDT

The mammalian target of rapamycin might prolong progression-free survival in patients who have already tried other targeted therapies.
Medscape Medical News

ASCO 2008: Genitourinary Cancer

Wed, 23 Jul 2008 12:00:00 EDT

Important new data about drug treatment of renal and prostate cancers, as reported at ASCO 2008, are highlighted by experts.
Medscape Hematology-Oncology

Advances in the Treatment of Renal Cell Carcinoma

Wed, 23 Jul 2008 15:09:14 EDT

Several important advances in targeted and other therapies for renal cell carcinoma are reviewed in this report from ASCO 2008.
Medscape Hematology-Oncology

New Guidelines About Diagnosis and Treatment of Children and Infants With Stroke

Wed, 23 Jul 2008 15:44:02 EDT

Mark Alberts, MD, discusses new guidelines concerning the diagnosis and treatment of children and infants who have a stroke in his videoblog.
Medscape Neurology & Neurosurgery

Race Not a Determinant of Outcome at One Year After PCI

Thu, 24 Jul 2008 09:51:01 EDT

African-American patients and Caucasian patients have similar 1-year outcome after percutaneous coronary intervention (PCI), but chronic kidney disease (CKD) has a significant adverse effect on mortality, investigators report.
Reuters Health Information

Reduced Creatinine Clearance and Microalbuminuria Both Predict Stroke

Thu, 24 Jul 2008 09:52:58 EDT

Impairment of the glomerular filtration rate (GFR) and the glomerular filtration barrier are independently associated with stroke, according to an analysis of data from the 1999-2004 National Health and Nutrition Examination Surveys (NHANES).
Reuters Health Information

Physicians for Sale: How Medical Professional Organizations Exploit Their Members

Mon, 21 Jul 2008 08:50:07 EDT

To improve the state of US healthcare, physicians need to rethink what their profession is and identify what they need to do to regain their professional integrity.
The Medscape Journal of Medicine

Gadolinium-Based Contrast Raises Nephrogenic Systemic Fibrosis Risk

Tue, 22 Jul 2008 11:21:11 EDT

Gadolinium-based contrast material used in magnetic resonance imaging (MRI) increases the risk for nephrogenic systemic fibrosis (NSF), according to a report in the June issue of the American Journal of Kidney Diseases.
Reuters Health Information

Building Physician Connectivity for e-Prescribing

Fri, 18 Jul 2008 08:53:10 EDT

Kevin Hutchinson, President and Chief Executive Officer of Prematics, Inc., in Vienna, Virginia, tells us how to move e-prescribing forward.
The Medscape Journal of Medicine

Kidney Disease Linked to Lower Medication Use Post-MI

Fri, 18 Jul 2008 17:00:00 EDT

Kidney disease is linked to lower medication use after myocardial infarction, but this is unlikely to explain the worse long-term outcomes, a new study suggests.
Medscape Medical News

Survival Impact of Vitamin D Therapy in Hemodialysis Patients

Thu, 17 Jul 2008 10:48:24 EDT

Lavinia Aura Negrea, MD, Assistant Professor of Medicine at Case Western University, reviews recent survival data and the role of vitamin D supplementation in patients with chronic kidney disease.
Medscape Nephrology

News From Clinical Trials in Multifactorial Hypertension

Thu, 17 Jul 2008 17:13:31 EDT

ASH 2008: Substudy and other data from the ON-TARGET, TRANSCEND, AASK, ACCORD, EXCEED, and ACCOMPLISH trials.
Medscape Cardiology

Astellas Wins Japan Approval for Once-Daily Formulation of Tacrolimus

Thu, 17 Jul 2008 18:20:14 EDT

Astellas Pharma Inc said on Thursday it had won approval to sell a new version of its key transplant drug in Japan, the second major region where it has gained approval although it is facing delays in the United States.
Reuters Health Information

Renal Transplant Ups Risk of Complications of Chronic Kidney Disease in Children

Thu, 17 Jul 2008 18:39:10 EDT

Anemia and hypertension occur more often in children and adolescents with chronic kidney disease (CKD) who have undergone a kidney transplant than in those with CKD in native kidneys, results of a study published in the June issue of the American Journal of Kidney Diseases indicate.
Reuters Health Information

Reverse Transcriptase Inhibitors Promising Against Renal Clear-Cell Carcinoma

Thu, 17 Jul 2008 11:26:19 EDT

The non-nucleoside reverse transcriptase (RT) inhibitors efavirenz and nevirapine induce cell differentiation and enhance the immunogenic phenotype in human renal clear-cell carcinoma (RCC), according to Italian researchers.
Reuters Health Information

Talactoferrin Promising Against Metastatic Kidney Cancer

Thu, 17 Jul 2008 11:27:27 EDT

Talactoferrin, a recombinant form of human lactoferrin, shows activity against metastatic renal cell carcinoma (RCC) in previously treated patients, according to a report in the July 1st issue of Cancer.
Reuters Health Information

Rituximab Plus IVIG Useful for Desensitization During Renal Transplantation

Thu, 17 Jul 2008 11:29:49 EDT

In kidney transplant candidates highly sensitized to HLA, treatment with rituximab plus intravenous immune globulin (IVIG) may cut anti-HLA antibody levels and improve transplantation rates, the results of an open-label, phase 1-2 study suggest.
Reuters Health Information

Oxalate in Renal Stone Disease: The Terminal Metabolite That Just Won't Go Away

Wed, 23 Jul 2008 15:38:59 EDT

Learn more about the function of oxalate and its potential roles in nephrolithiasis and nephrocalcinosis in this review of animal studies.
Nature Clinical Practice Nephrology

Sensitivity of International Classification of Diseases Codes for Hyponatremia Among Commercially Insured Outpatients in the United States

Mon, 21 Jul 2008 15:08:21 EDT

Should International Classification of Diseases Codes be used to identify outpatient hyponatremia incidence? Uncover what these study authors found in a commercially insured population.
BMC Nephrology