HIV/AIDS News

 
 
 
 

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  • Stable Soft-Tissue Filler Stimulates an Immune Response Calcium hydroxylapatite, which has been approved for facial cosmetic indications, stimulates an immune response with lymphocytic infiltration and foreign body giant cell formation.
  • Abacavir May Be Less Effective in HIV Patients With High Viral Load In the ACTG 5202 trial, abacavir may have lead to a higher rate of virologic failure in patients with a high viral load, although a separate company-supported trial shows a different view.
  • Abacavir May Increase Risk for CVD in Subset of Patients In an analysis of the SMART trial, long-term use of abacavir was associated with increased cardiovascular disease risk and higher levels of IL-6 and hs-CRP in a subset of patients. However, a company-funded study found the opposite.
  • Progress Made on 3 Second-Generation NNRTIs New second-generation nonnucleoside reverse transcriptase inhibitors, some of which show activity against HIV strains resistant to current first-line therapy, continue to show promise.
 
 
 
 
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