BMC Nephrology publishes original peer-reviewed research articles in all aspects of the prevention, diagnosis and management of kidney and associated disorders, as well as related molecular genetics, pathophysiology, and epidemiology. All research articles in BMC Nephrology, and other BioMed Central journals, are made available under an open access license, allowing free access, redistribution and reuse.
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Age-Related Associations of Hypertension and Diabetes Mellitus With Chronic Kidney Disease
Among US adults, diabetes mellitus and hypertension are associated with CKD and albuminuria regardless of age.
Journal Article, October 2009
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Accuracy and Limitations of Equations for Predicting the Glomerular Filtration Rate During Follow-Up of Patients With Non-Diabetic Nephropathies
Are these equations accurate in patients with non diabetic nephropathies and deteriorated renal function?
Journal Article, June 2009
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Comparison of Markers of Oxidative Stress, Inflammation and Arterial Stiffness Between Incident Hemodialysis and Peritoneal Dialysis Patients An Observational Study
The effects of peritoneal dialysis and hemodialysis on arterial stiffness, vascular function, myocardial structure and function, oxidative stress and inflammation are compared.
Journal Article, March 2009
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The Importance of Iron in Long-Term Survival of Maintenance Hemodialysis Patients Treated With Epoetin-Alpha and Intravenous Iron: Analysis of 9.5 Years of Prospectively Collected Data
Erythropoietin and iron play a role in the genesis of the anemia of chronic kidney disease, but how much do they affect survival?
Journal Article, February 2009
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The Importance of Iron in Long-Term Survival of Maintenance Hemodialysis Patients Treated With Epoetin-Alfa and Intravenous Iron: Analysis of 9.5 Years of Prospectively Collected Data
Epoetin-alfa and intravenous irons effects on survival and other variables related to iron status are examined.
Journal Article, February 2009
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Preventing AVF Thrombosis: the Rationale and Design of the Omega-3 Fatty Acids (Fish Oils) and Aspirin in Vascular Access OUtcomes in REnal Disease (FAVOURED) Study
The primary failure rate of an AVF ranges between 20 to 54 percent. This study is designed to determine whether primary AVF surgery outcomes can be improved by the use of aspirin and/or fish oils.
Journal Article, January 2009
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NPHS2 Variation in Focal and Segmental Glomerulosclerosis
Focal and segmental glomerulosclerosis (FSGS) is the most common histologic pattern of renal injury seen in adults with idiopathic proteinuria.
Journal Article, September 2008
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Serum Free Light Chain Measurement Aids the Diagnosis of Myeloma in Patients With Severe Renal Failure
Monoclonal free light chains (FLCs) frequently cause rapidly progressive renal failure in patients with multiple myeloma. Immunoassays which provide quantitative measurement of FLCs in serum, have now been adopted into screening algorithms for multiple myeloma .
Journal Article, September 2008
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Association of Kidney Function With Inflammatory and Procoagulant Markers in a Diverse Cohort: A Cross-Sectional Analysis From the Multi-Ethnic Study of Atherosclerosis (MESA)
Six inflammatory and procoagulant biomarkers were correlated with kidney function measures in multi-ethnic patients to replicate results from similar studies in non-diverse populations.
Journal Article, August 2008
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Oxpentifylline Versus Placebo in the Treatment of Erythropoietin-resistant Anaemia: A Randomized Controlled Trial
Anemia is a common problem in chronic kidney disease (CKD) but treatments are only marginally effective. Oxpentifylline is being studied as a new therapy for erythropoietin-resistant anaemia.
Journal Article, August 2008
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Sensitivity of International Classification of Diseases Codes for Hyponatremia Among Commercially Insured Outpatients in the United States
Should International Classification of Diseases Codes be used to identify outpatient hyponatremia incidence? Uncover what these study authors found in a commercially insured population.
Journal Article, June 2008
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The Lipid Lowering and Onset of Renal Disease (LORD) Trial: a Randomized Double Blind Placebo Controlled Trial Assessing the Effect of Atorvastatin on the Progression of Kidney Disease
How does atorvastatin affect kidney disease progression? Discover more about the relationship between dyslipidemia and chronic kidney disease.
Journal Article, March 2008
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A Systematic Review Of Patient And Health System Characteristics Associated With Late Referral In Chronic Kidney Disease
The aim of this systematic review is to identify patient and health system characteristics associated with late referral of patients with chronic kidney disease to nephrologists.
Journal Article, February 2008
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A Systematic Review Of The Prevalence And Determinants Of Nonadherence To Phosphate Binding Medication In Patients With End-stage Renal Disease
There is a need to establish the level of nonadherence to phosphate binding medication in renal dialysis patients and identify the factors associated with it.
Journal Article, January 2008
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Analgesics Use And ESRD In Younger Age: A Case-control Study
An ad hoc peer-review committee was jointly appointed by Drug Authorities and Industry in 1999/2000 to review the evidence for a causal relation between phenacetin-free analgesics and nephropathy.
Journal Article, December 2007
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Prognosis and Serum Creatinine Levels In Acute Renal Failure at the Time of Nephrology Consultation: An Observational Cohort Study
The aim of this study is to evaluate the association between acute serum creatinine changes in acute renal failure using the RIFLE criteria.
Journal Article, September 2007
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Clinical Proof-Of-Concept Trial To Assess The Therapeutic Effect Of Sirolimus In Patients With Autosomal Dominant Polycystic Kidney Disease: SUISSE ADPKD Study
The first randomized controlled trial to examine the effectiveness, safety and tolerability of sirolimus to retard disease progression in ADPKD is designed and discussed.
Journal Article, September 2007
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Strategies To Reduce Clinical Inertia In Hypertensive Kidney Transplant Recipients
Many kidney transplant recipients have hypertension. Elevated systolic blood pressures are associated with lower patient and kidney allograft survival.
Journal Article, July 2007
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The Effect of Gender, Age, and Geographical Location on the Incidence and Prevalence of Renal Replacement Therapy in Wales
This study used a cross sectional survey to examine the effect of gender, age, and geographical location on the population prevalence of renal replacement therapy provision in Wales.
Journal Article, January 2007
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Reliability and Validity of the ESRD Symptom Checklist -- Transplantation Module in Norwegian kidney transplant recipients
The Norwegian version of a questionnaire designed to assess quality of life in kidney transplant recipients, the End-Stage Renal Disease Symptom Checklist -- Transplantation Module is validated.
Journal Article, November 2006
